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Collectively, the lactatelactylation axis represents a unifying mechanistic framework linking metabolic flux to epigenetic regulation in neurological disorders and may serve as a promising source of diagnostic biomarkers and precision therapeutic targets

In addition to inducing HF by promoting atherosclerotic progression, elevated plasma TMAO levels may accelerate myocardial hypertrophy, exacerbate mitochondrial dysfunction, and induce transverse-tubule (T-tubule) remodeling in cardiomyocytes (93)

[DOI] [PMC free article] [PubMed] [Google Scholar] 13.Mayo KE, Miller LJ, Bataille D, Dalle S, Gke B, Thorens B, et al

Start your intake How Hypothyroidism Affects Weight Management Hypothyroidism occurs when the thyroid gland produces insufficient thyroid hormone, slowing nearly every metabolic process in the body